The Next Evolution in Skin Renewal + Regeneration: Why Your Nighttime Skincare Routine Matters

The right nighttime skincare routine can do more than hydrate, it can support skin renewal, repair, and regeneration while you sleep. Discover how Hydrinity’s RetaXome™ Retinal Boost Treatment Pads and CÉLTHERA™ Advanced Overnight Repair Cream help visibly improve the look of texture, tone, firmness, elasticity, hydration, and overall skin quality.

Your skin doesn’t stop working when you go to sleep. In fact, nighttime is an important window for supporting the skin’s natural renewal and recovery processes.

Throughout the day, skin is exposed to UV radiation, pollution, oxidative stress, and other environmental stressors. At night, the skin enters a more restorative phase, making your evening skincare routine an opportunity to support hydration, barrier recovery, and visible skin renewal.

That’s where targeted nighttime skincare comes in.

Rather than simply layering on more products, a well-designed nighttime routine can focus on two complementary priorities: renewing the appearance of skin and supporting its recovery.

That philosophy is at the heart of Hydrinity’s newest innovations: RetaXome Retinal Boost Treatment Pads and CÉLTHERA Advanced Overnight Repair Cream, two next-generation formulas designed to elevate the nighttime skincare experience.

Why Is Nighttime Skincare Important?

Your skin follows a circadian rhythm, meaning its functions change throughout the day and night. During nighttime, restorative processes become more active, creating an ideal opportunity to support the skin with targeted treatments.

A thoughtful nighttime skincare routine can help support:

• Skin renewal and cellular turnover
• Hydration and moisture retention
• A firmer looking appearance
• Recovery from daily environmental stressors
• A smoother, more refined-looking texture
• Skin barrier recovery

The goal isn’t necessarily to use more products. It’s to choose formulas that complement the skin’s nighttime needs and address specific concerns in a strategic routine.

The Next Evolution in Skin Renewal + Regeneration

Hydrinity’s latest nighttime innovations take a two-part approach to skin renewal and regeneration.

RetaXome Retinal Boost Treatment Pads are designed to resurface and renew the appearance of skin, while CÉLTHERA Advanced Overnight Repair Cream is designed to replenish, moisturize, and support skin quality overnight.

Meet RetaXome Retinal Boost Treatment Pads: One Treatment. Every Skin Story.

RetaXome Retinal Boost Treatment Pads are a next-generation at-home treatment peel pad that combines the retinal technology behind Hydrinity’s award-winning RetaXome™ Daily Retinal Hydrator with a proprietary ABP 5-Acid Complex and Supercharged HA in a single treatment pad.

The result is a complete skin renewal treatment designed to accelerate the appearance of skin renewal, clear congestion, refine visible texture, and support hydration and barrier recovery.

What’s Inside RetaXome Retinal Boost Treatment Pads?

RetaXome™ Technology
Hydrinity’s proprietary retinal uses stabilized, encapsulated retinal delivered through a proprietary biomimetic exosome delivery system. Retinal helps support visible skin renewal and improve the appearance of fine lines, texture, and overall skin quality.

ABP 5-Acid Complex
A proprietary, synergistic combination of five exfoliating acids helps resurface the skin and visibly refine pores, tone, and texture.

Oligopeptide-10
Helps reduce acne causing bacteria and minimize the appearance of inflammation associated with breakouts.

Supercharged HA
Dual-weight hyaluronic acid helps provide hydration while supporting the skin barrier.

Ectoin + Glyceryl Glucoside
Help soothe and hydrate skin while supporting barrier recovery.

What Results Can You Expect?

In clinical evaluation, RetaXome Retinal Boost Treatment Pads demonstrated visible improvements over time, including:

• 38.5% improvement in the appearance of hyperpigmentation in as little as 2 weeks
• 78% improvement in the appearance of redness at 12 weeks
• 78% improvement in smoother-looking wrinkles and softer-looking lines at 12 weeks
• 77% improvement in the appearance of pores at 12 weeks
• 77% improvement in skin tone evenness at 12 weeks

*Individual results may vary.

Meet CÉLTHERA™ Advanced Overnight Repair Cream: The Future of Overnight Skin Regeneration Has Arrived.

After a skin-renewing treatment, replenishment matters.

CÉLTHERA Advanced Overnight Repair Cream is a clinically advanced repairing and moisturizing cream designed to work with the skin overnight. It combines first-of-its-kind ExoEGF™ Technology, an exosome-delivered vegan Epidermal Growth Factor, Centella Secretomes, and NAD+ Boost Technology to work beyond traditional hydration.

The formula is designed to visibly improve firmness, elasticity, texture, and overall skin quality while supporting biological processes associated with healthier, younger-looking skin.

What’s Inside CÉLTHERA™?

ExoEGF™ Technology
An exosome-delivered vegan Epidermal Growth Factor designed to support the

NAD+ Boost Technology
Helps boost the skin's own NAD+ levels to promote cellular energy and improve overall skin vitality.

Centella Secretomes
A concentrated skin-supporting technology designed to complement the skin’s natural repair processes and support healthier-looking skin.

Senolytic Renewal Complex
Helps target aging “zombie” cells as part of a comprehensive approach to supporting healthier cellular function.

Multi-Ceramide Barrier Complex + Ectoin
Helps replenish essential lipids, improve moisture retention, and support a stronger, healthier-feeling skin barrier.

What Results Can You Expect?

In clinical evaluation, CÉLTHERA demonstrated visible improvements in skin appearance, hydration, and firmness, including:

• 100% of participants showed improvement in overall skin appearance and hydration at 2 weeks
• Visible improvement in fine lines and wrinkles at 2 weeks
• Improved hydration and glow at 4 weeks
• 85% improvement in the appearance of firmer skin at 8 weeks

*Individual results may vary. 

The Future of Nighttime Skincare Has Arrived

Your nighttime skincare routine is more than the last step of your day. It’s an opportunity to support the skin’s natural processes with targeted formulas designed for what your skin needs overnight.

RetaXome Retinal Boost Treatment Pads deliver a next-generation at-home peel treatment that combines retinal technology, a proprietary ABP 5-Acid Complex, and Supercharged HA to support visible skin renewal.

CÉLTHERA Advanced Overnight Repair Cream goes beyond traditional hydration with ExoEGF™ Technology, Centella Secretomes, and NAD+ Boost Technology to support overnight repair, hydration, firmness, elasticity, and overall skin quality.

Together, they represent The Next Evolution in Skin Renewal + Regeneration.

Resurface. Repair. Regenerate. Wake up to skin that looks renewed.

Frequently Asked Questions About Nighttime Skincare

Why is nighttime skincare important?

Nighttime is an important period for the skin’s natural restorative processes. A targeted nighttime skincare routine can help support skin renewal, hydration, barrier recovery, and overall skin quality while you sleep.

What should I use after a retinal treatment?

After a retinal treatment, a moisturizing, barrier-supporting cream can help replenish hydration and support skin comfort. CÉLTHERA Advanced Overnight Repair Cream is designed to provide overnight moisturizing, repairing, and barrier support.

Can I use RetaXome Retinal Boost Treatment Pads and CÉLTHERA together?

RetaXome Retinal Boost Treatment Pads and CÉLTHERA are designed around complementary nighttime skincare goals: visible skin renewal and overnight replenishment. Follow the application instructions for each product and adjust frequency based on your skin’s individual needs. Because everyone’s skin type is different, we also recommend consulting your skincare professional before combining both products in your routine. 

How long does it take to see results from nighttime skincare?

Results vary by individual and product. In clinical evaluations, both RetaXome Retinal Boost Treatment Pads and CÉLTHERA demonstrated visible improvements within the first few weeks, with additional improvements observed over longer evaluation periods.

What does overnight skin regeneration mean?

Overnight skin regeneration refers to supporting the skin’s natural nighttime renewal, recovery, hydration, and restorative processes. Targeted nighttime skincare can complement these processes by providing ingredients and technologies designed to support visible improvements in skin quality.

What is the difference between skin renewal and skin regeneration?

Skin renewal generally refers to processes associated with the turnover and resurfacing of skin, while skin regeneration encompasses broader processes that support the skin’s structure, function, hydration, and overall quality. A comprehensive nighttime routine can address both through targeted treatment and replenishment.

Discover the Next Evolution in Skin Renewal + Regeneration

Hydrinity products are available only on our website or through participating Hydrinity clinical professionals; you can find your nearest one at https://www.hydrinity.com/pages/find-a-professional